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Clarity LIMS Support

As Illumina's Clarity LIMS Implementation Partner, we specialize in BaseSpace Clarity LIMS implementations and customizations.

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Client Overview

As the primary professional services partner for Illumina’s Clarity LIMS, Semaphore Solutions has established itself as the leader in LIMS implementation, integration, and support for Next-Generation Sequencing (NGS) laboratories. Our clients include public health organizations, research institutions, and clinical genomics labs that require a robust, scalable, and highly configurable laboratory information management system.

CHALLENGES

Many laboratories using Clarity LIMS face challenges customizing workflows, integrating systems, and maintaining performance at scale—especially when operating in regulated environments.

Solution Overview

With over a decade of experience as Illumina’s premier Clarity LIMS services provider, Semaphore Solutions has developed proven methodologies and proprietary tools to streamline implementation and support. Our approach includes:

  • ‍Expert-Led Implementations – Our team of former Illumina professionals, field application scientists, and software engineers has accumulated over 60 person-years of Clarity LIMS experience.‍
  • Custom Workflow Design – We develop tailored LIMS workflows that align with laboratory operations, ensuring seamless automation and compliance with industry best practices.‍
  • Advanced Integration Capabilities – We specialize in integrating Clarity LIMS with instruments, data warehouses, and enterprise systems, and LIS, to create end-to-end informatics solutions.‍
  • Scalable Support Services – Our ongoing support services ensure that clients receive rapid troubleshooting, proactive maintenance, and system upgrades to keep their LIMS running at peak performance.

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Key Outcomes and Measurable Results

Semaphore Solutions has consistently delivered

Through our extensive portfolio of Clarity LIMS projects, Semaphore Solutions has consistently delivered: Faster, more efficient implementations that minimize downtime and maximize adoption. Seamless integration with laboratory and enterprise systems, reducing manual data entry and errors. Optimized performance and scalability, ensuring Clarity LIMS can support increasing sample volumes. Long-term support and enhancements that allow labs to evolve their LIMS without disrupting operations.

Key Outcomes and Measurable Results

Semaphore Solutions has consistently delivered

Through our extensive portfolio of Clarity LIMS projects, Semaphore Solutions has consistently delivered: Faster, more efficient implementations that minimize downtime and maximize adoption. Seamless integration with laboratory and enterprise systems, reducing manual data entry and errors. Optimized performance and scalability, ensuring Clarity LIMS can support increasing sample volumes. Long-term support and enhancements that allow labs to evolve their LIMS without disrupting operations.

“Using software to differentiate our business has been part of Adaptive’s strategy since its inception. We don’t do a lot of outsourcing, but our relationship with Semaphore has been instrumental to our success. They help us scale up quickly when needed, and their experience with Clarity and NGS lab process is a key resource we use regularly.”
Sean Nolan, Chief Technology Officer, Adaptive Biotechnologies

In-Depth Analysis

Semaphore’s unparalleled experience in Clarity LIMS services comes from years of deep collaboration with Illumina and leading genomics labs worldwide. Our involvement in large-scale projects—including the UK’s 100,000 Genomes Project—has given us unique insight into the challenges of scaling Clarity LIMS for high-throughput, regulated environments.

Unlike generic LIMS consultants, our team has been embedded in every stage of Clarity LIMS evolution—from its earliest implementations to its latest updates. This expertise allows us to:

  • Preemptively identify system inefficiencies and limitations, ensuring proactive solutions rather than reactive fixes.‍
  • Leverage proprietary software tools designed specifically for Clarity LIMS projects, reducing the time and cost of configuration.‍
  • Provide unmatched continuity and efficiency, ensuring that Clarity LIMS evolves in step with laboratory needs rather than requiring costly and disruptive overhauls.

Semaphore Solutions has supported dozens of laboratories with Clarity LIMS, gaining a unique understanding of the common pain points labs experience during implementation and operation. Key issues include:

  • Workflow Complexity: Labs often need to tailor Clarity LIMS to accommodate custom assays, clinical reporting structures, or multi-step review processes. These configurations require domain expertise and deep system knowledge.
  • System Integration: Integrating Clarity LIMS with laboratory instruments (e.g., Hamilton liquid handlers), other LIMS systems (like StarLIMS), EMRs, or analytics platforms is non-trivial and requires careful API and schema coordination.
  • Scalability & Performance: As labs scale throughput, data volume and concurrent processing demands increase. Without the right configuration strategies, performance bottlenecks can threaten turnaround times and data integrity.
  • Ongoing Maintenance: Labs operating in regulated environments must maintain validated states through updates and enhancements. Balancing agility with compliance is a frequent challenge, especially when internal teams lack dedicated Clarity LIMS resources.

Semaphore addresses these issues through a combination of deep product experience (over 60 person-years), proprietary implementation accelerators, and a team that includes former Illumina LIMS engineers. This expertise allows us to deliver customized, compliant, and scalable solutions tailored to each lab’s unique operational context.

Our partnership model allows clients to transition from reactive, ad-hoc support to a fully managed and optimized LIMS ecosystem, aligning their informatics infrastructure with long-term research and clinical goals.

Why it Matters

In a landscape where data integrity, workflow automation, and regulatory compliance are mission-critical, having the right informatics partner can make or break a laboratory’s success. Semaphore Solutions is not just a vendor—we are the driving force behind the most successful Clarity LIMS implementations worldwide.

Our proven track record, deep domain expertise, and commitment to innovation allow us to support Clarity LIMS customers with unparalleled efficiency and reliability. Whether it’s a new implementation, a complex integration, or ongoing system optimization, our expertise ensures that laboratories can focus on scientific discovery and patient impact—not software limitations.

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