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See how Semaphore implemented an integrated LIMS for a large scale Molecular & Genomic Pathology Hospital Laboratory
Contact usThis large scale Molecular and Genomic Laboratory is part of a hospital system that is ranked within the top 15 in the United States, and as such is responsible for the analysis of a high volume of clinically significant samples. This highly complex, state of the art laboratory runs many different types of analyses and is staffed with a large, multidisciplinary team.
Like many other complex genomic laboratories, this lab found that tasks such as repetitive paperwork, data entry, and by-hand calculations took time away from lab technicians doing their actual job: analyzing clinical samples. They needed a LIMS that aligned with their workflow while eliminating redundancy and streamlining process. They also required a LIMS that could be fully integrated into their existing EMR and LIS. Semaphore worked closely with the lab management staff to help them meet all of these requirements. Through teamwork and an open, iterative process, Semaphore has provided a custom solution that spans the entire laboratory workflow.
Genomic laboratories have complex workflows. From accessioning through to analysis, the number of possible interactions between sample, staff, and instrument can be overwhelming. Many labs purchase Laboratory Information Management System (LIMS) software planning to streamline, regulate, and document workflows. LIMS systems in these environments are sometimes employed directly out of the box with great success, but often require extra configuration to best support the specific needs of complex genomic laboratories.
Semaphore Solutions understands that when it comes to LIMS, one size does not fit all. As an Illumina Partner, Semaphore specializes in BaseSpace Clarity LIMS implementation, configuration, and support. With years of experience in Clarity configuration, Semaphore’s development team is expert at building laboratory solutions. Our team members are also experts at integrating LIMS with Electronic Medical Record systems (EMR’s) via HL7.
A major US hospital molecular diagnostic laboratory found their needs exceeded out of the box LIMS capabilities. Semaphore Solutions has worked with laboratory stakeholders to design and deliver significant customizations to BaseSpace Clarity LIMS. Semaphore continues to work with the lab, expanding and evolving LIMS in this complex and dynamic environment.
This Large Scale Molecular & Genomic Pathology laboratory required a customized, fully integrated LIMS to track and manage complex daily workflow. Semaphore’s dedicated development team were able to meet their needs by creating custom solutions across all stages of the laboratory workflow.
This Large Scale Molecular & Genomic Pathology laboratory required a customized, fully integrated LIMS to track and manage complex daily workflow. Semaphore’s dedicated development team were able to meet their needs by creating custom solutions across all stages of the laboratory workflow.
Accessioning: Semaphore’s team is highly proficient in HL7, and integrated LIMS with pre-existing Laboratory Information Systems (LIS’s) and Electronic Medical Record systems (EMR’s). The integration with the pre-existing LIS enables Accessioning staff to continue working with the software they already know and trust, but with the advanced functionality of BaseSpace Clarity LIMS.
Sample Processing: All extraction protocols are batched to increase efficiency and reduce lag time. A barcode is generated for each sample to allow for easy re-extraction at a later date.
Analysis Preparation: Semaphore’s customizations automate plate assignments, reagent calculations, and dissolution tables. The automation of repetitive tasks reduces the potential for human error while saving time and money.
Benchtop Support: Bench notes are automatically generated and displayed on tablets to ensure placement tables, calculations, notes, and reminders are kept handy at each workstation. Comprehensive, easily accessible bench notes enable lab technicians to remain focused on the task at hand.
Instrument integration: Bi-directional instrument integration enables lab staff to skip data entry and get straight to work. Output automatically feeds back into the LIMS, enabling quick turnaround between testing and delivering results.
Internal Reports: An internal tracking report is generated for each sample, simplifying retroactive reporting of analytic factors. Tracking reports are especially useful for audits and accreditation.
Technologies: PCR, NanoDrop, Mass Spec, HL7, Assays
In the realm of molecular diagnostics, the seamless integration of Laboratory Information Management Systems (LIMS) with existing Electronic Medical Record (EMR) and Laboratory Information Systems (LIS) is paramount. This case exemplifies how a top-tier hospital’s molecular and genomic pathology laboratory partnered with Semaphore Solutions to customize and enhance their LIMS, effectively bridging the gap between complex laboratory workflows and clinical data management systems.
By addressing challenges such as redundant data entry, manual calculations, and the need for real-time data synchronization, the collaboration led to a more efficient and error-resistant laboratory environment. The tailored LIMS solution not only streamlined processes but also ensured compliance with regulatory standards, ultimately contributing to improved patient care. This case underscores the critical role of bespoke informatics solutions in modern healthcare settings, where precision and efficiency are essential for delivering timely and accurate diagnostic results.
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