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The Manifest Import Tool: A Hand-Crafted Solution for a Sample Accessioning Bottleneck

Discover how Semaphore Solutions partnered with a leading CRO to automate sample data import, enhancing efficiency and data quality.

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Client Overview

A contract research organization (CRO) specializing in sequencing for scientific research and clinical trials.

CHALLENGES

The lab faced time-consuming manual processes to standardize diverse sample manifests for LIMS accessioning, leading to inefficiencies and potential errors.

Solution Overview

Initial Assessment

Semaphore collaborated closely with the CRO's laboratory team, employing a collaborative, agile process. Through periodic demos of completed work, both teams developed mutual trust, which was key to accelerating the project's success.

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Tailored Solution Development

Semaphore designed and built a manifest import tool application to address manifest format inconsistencies during sample accessioning. The application featured a custom user interface that streamlined the mapping of columns in the customer manifest file to the appropriate LIMS fields, significantly reducing the time required to accession samples and improving data quality.

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Implementation and Integration

The application was integrated into the lab's existing workflows, with validation measures built into the application to ensure completeness and accuracy of data, as well as adherence to HIPAA regulations.

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Post-Implementation Support

Semaphore thoroughly trained the CRO lab team in using the application. During the warranty period, when the project revealed gaps in the client's workflows, Semaphore helped their team identify and overcome the issues, ensuring smooth operation. Additionally, Semaphore trained the internal development team to maintain the application independently.

Key Outcomes and Measurable Results

Enhanced Productivity

The new application provided a significantly faster method for importing patient sample data into the LIMS, reducing manual effort and associated errors.

Improved Data Quality

The lab reported that the application is easy to use and has become a valuable tool in their day-to-day work, leading to improved data quality entering the LIMS.

Key Outcomes and Measurable Results

Enhanced Productivity

The new application provided a significantly faster method for importing patient sample data into the LIMS, reducing manual effort and associated errors.

Improved Data Quality

The lab reported that the application is easy to use and has become a valuable tool in their day-to-day work, leading to improved data quality entering the LIMS.

“Semaphore provides software expertise for Helix’s Clarity LIMS implementation. They have provided excellent project management, technical leadership, and quality software development that was crucial to the successful launch of our high volume lab. It's exciting to work with such an attentive and collaborative team, especially during complex design and implementations."
Tony Le, Product Manager, Helix

In-Depth Analysis

Semaphore’s partnership with the CRO highlights its expertise in addressing lab informatics challenges with tailored solutions. By identifying inefficiencies in sample data processing, Semaphore designed a custom manifest import tool to automate the standardization of diverse sample manifests. The tool integrates seamlessly with the LIMS and includes validation measures to ensure data completeness, accuracy, and HIPAA compliance.

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Through an iterative development process with regular client feedback, Semaphore delivered a solution aligned with the lab’s goals. Comprehensive training empowered the CRO’s team to operate and maintain the tool independently, ensuring long-term success. The automation reduced manual effort, improved data quality, and positioned the lab to scale operations effectively while focusing on high-value scientific work. This case demonstrates Semaphore’s ability to transform complex workflows into streamlined, future-ready systems.

Why it Matters

Addressing Industry Challenges

Labs performing sequencing frequently face the challenge of receiving sample manifests in various formats, each requiring significant manual effort to standardize for LIMS accessioning. These inefficiencies not only slow operations but also increase the risk of errors in data entry, which can compromise overall lab quality. Semaphore’s custom manifest import tool directly addresses this pain point by automating the process, ensuring consistent data standardization, and significantly reducing the time and effort required for accessioning. This solution demonstrates Semaphore's ability to engineer tools that align with the unique operational demands of high-throughput labs while maintaining compliance and data integrity.

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Demonstrating Effective Collaboration

The successful partnership between Semaphore and the CRO exemplifies the importance of trust, communication, and expertise in developing transformative lab solutions. Semaphore’s collaborative approach, which involved iterative feedback and periodic demos, ensured the final product met the lab's exact needs. Beyond delivering the tool, Semaphore’s training empowered the lab team to maintain and optimize the system independently, ensuring long-term value. This case underscores Semaphore's commitment to fostering strong client relationships and delivering solutions that not only solve immediate problems but also support future scalability and innovation.

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